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Symplocamide A
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Symplocamide A : ウィキペディア英語版
Symplocamide A

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Symplocamide A is a newly discovered (2008) 3-amino-6-hydroxy-2-piperidone (Ahp) cyclodepsipeptide that has been isolated from a marine cyanobacteria in Papua New Guinea, which has only been identified at the genus level (''Symploca''). Cyanobacteria, both freshwater and marine, are known as producers of diverse protease inhibitors that may be used to treat diseases, such as HIV, and some forms of cancer. Research on symplocamide A has shown that it is a strong serine protease inhibitor and has a high level of cytotoxicity to cancer cells when used in vitro. As of the time of this writing, its use as a treatment on human participants has not been done and future study will have to be done before any human testing can be commenced.
==Origin==
Symplocamide A has only recently been discovered when scientists were looking for various marine cyanobacterium in order to extract possible protease inhibitors not seen in freshwater cyanobacterium. It was obtained from ''Symploca'' sp. in Papua New Guinea, and the genus has not been recorded in the literature. Using nuclear magnetic resonance (NMR), the molecular formula (C46H71BrN10O13) and structure were elucidated.〔 More data will need to be gathered, as without a genus being described by the discovery of symplocamide A, recreation of the data cannot be confirmed.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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